VROC® initium one plus performance with 96-well plate sealing film

The VROC^® initium one plus automated viscometer has the option to use a 96-well plate in the temperature-controlled sample tray. Sealing films are required for the well plate to prevent evaporation and contamination. To be compatible with the autosampler syringe used for loading, the film must be easily punctured without coring or fracturing which could lead to clogging along the flow path or in the microfluidic channel. 

We have identified a polytetrafluoroethylene (PTFE) film designed to be punctured without coring or needle clogging (J.G. Finneran Associates, Inc). The PTFE film is compatible with aqueous solutions and expected to have excellent chemical resistance to a broad range of organic solvents. To assess the performance of the PTFE sealing film, an extensive test was conducted, monitoring for consistent puncturing of the film, loaded volume, and viscosity value.

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