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Why Measure Intrinsic Viscosity?

Intrinsic Viscosity is a parameter used to determine the molecular size, weight, structure, and interactions among proteins, polymers, or macromolecules. Applications pertinent to polymerization, degradation, interaction, and the stability of molecules all benefit from measuring Intrinsic Viscosity.

 

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Intrinsic Viscosity: Know Your Molecules

Intrinsic viscosity analysis can be used to examine the molecular structure and interactions of molecules in suspension. It is also a useful parameter for proteins, polymers, and other colloidal suspensions. Intrinsic viscosity measures a solute’s contribution to viscosity at infinite dilution and can be used to calculate molecular size, molecular weight, and  stability of proteins, polymers, or macromolecules interact in solution.

Measurement of intrinsic viscosity parameters is considered to be a more reliable method for understanding these complex phenomena than conventional light scattering.

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Research & Development

Intrinsic viscosity can help R&D scientists develop better polymer products by characterizing the size, weight, and interactions of the molecules early.

Polymers, composed of macromolecules, vary significantly depending on the length of the final chain of monomers. Intrinsic viscosity helps to determine this behavior without running through production processes allowing for the selection of the best polymer for product development.

Intrinsic Viscosity Graph - Huggins and Kraemer

Quality Control

Ensure that quality by adding intrinsic viscosity as a QC parameter.

Verify the molecular structure during or after production quickly and easily with microVISC PRO.

Test Tubes - Minimized

Why RheoSense?

Intrinsic viscosity is critical in polymer research, development, production, and quality control. Traditional methods, such as manual glass capillary viscometers, are difficult to use, time-consuming, and prone to variations from operator to operator.

RheoSense microVISC PRO viscometer offers an advanced solution improving data quality and productivity even for highly volatile samples.

  • Walk Up Ready – No training required
  • High Throughput – More data in less time
  • Fast, Precise Temperature Control - Know how your polymers react to heat
  • Continual Measurements - No cleaning needed
  • Cost-Effective – Performance without the premium price

Intrinsic Viscosity Application Notes

Intrinsic Viscosity of PEO - App Note CTA Tile
Intrinsic Viscosity - Protein Therapeutics
SoP - Intrinsic Viscosity

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