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Viscosity in Biopharmaceuticals


Where does viscosity fit when it comes to the Pharmaceutical and Biotechnology Industry?

Protein-based drugs are the fastest growing class of drugs for the treatment of many diseases in humans, ranging from cancer to Alzheimer’s disease. Accurate viscosity values of proteins are essential in understanding behavior, designing delivery systems, and accurately determining particle size/hydrodynamic radius. 

VROC® powered viscometers deliver accurate and reliable viscosity results that are required to understand behaviors of antibodies and other proteins. By applying a wide range of viscosities and shear rates, you can gain a full length range of insight into your proteins.

Remember VROC® technology :

  • Smallest sample volumes
  • Direct shear rate control
  • First principle or true viscosity 

Check out all of our application notes separated into major topics: 

  • Formulation
  • Protein Screening
  • Antibody Therapeutics
  • Drug Delivery
  • Protein Stability
  • RNA Therapeutics
  • Hydrodynamic Radius
  • Whole Blood/Blood Plasma/Blood Serum
  • Ophthalmic Solutions

Formulation


 

Protein Formulation Requires Stability & Efficacy

Working with various protein candidates, buffers, adding excipients, etc, check out the application notes that we have published that are important to formulation.

 

Whole Blood/Blood Plasma/Blood Serum/Synovial Fluid


Hemodynamics

Fluid dynamics in blood flow can help understand flow behavior when it comes to diagnostics and treatment of various conditions. 

 

Opthalmic Solutions


Eye Drops

Eye drops or opthalmic solutions are a good example of where shear rates are a large contributing factor. 

 

RNA Therapeutics


RNA Therapies 

RNA Therapies have been used for high-impact drug development. RNA Therapy plays in cellular activity and thus have been an advantage over small and large molecule compound therapies in certain ways.

 

Antibody Therapeutics


Protein Therapeutics

Antibody therapeutics, an alternative method from RNA Therapeutics, is also equally viable when it comes to development combat methods against serious illnesses. See what factors will be important and what you should understand if you are in the industry.

 

Cell Culture


Cell Culture Media

Cell culture media is a complex fluid composed of nutrients required for cells to grow, proliferate, and differentiate.

 

 

Biodegradable Polymers


Biodegradable Polymers

Biodegradable polymers are compounds that break down after their intended use, resulting in gases and carbon sources that microorganisms can digest.

Lipids


Lipids Nanoparticles

Learn More About Protein Viscosity

 

 


 

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