Injection is a common delivery method for monoclonal antibody (mAb) based therapeutics.
There are multiple factors to consider when designing and executing viscosity measurements to be used as a predictive tool for the delivery of mAb therapeutics.
In this application note, shear rate dependent viscosity data was collected with the VROC® initium one plus for eighteen mAb formulations to predict the injection force and compare to the corresponding injection or glide force measurement data. The predictions were made with both a generalized non-Newtonian model and that for a Newtonian fluid using the low shear plateau viscosity.
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