<img height="1" width="1" style="display:none;" alt="" src="https://dc.ads.linkedin.com/collect/?pid=510762&amp;fmt=gif">

 

 

 

 

Take Control of Your Formulation Process

Concentration Dependence - Polymers
 

Viscosity of Thermo-sensitive Pharmaceutical Excipients

 

In this application note, viscosity profiles as a function of temperature where formulations including a common pharmaceutical excipient can exhibit a maximum in viscosity which is highly sensitive to the level of Poloxamer added. This study illustrates how a modest 1% increase in weight fraction significantly alters both the magnitude of the viscosity maximum and the temperature at which it occurs. Viscosity measurements are essential when optimizing formulation composition to achieve the desired flow behavior and temperature dependence.

Data-1

Poloxamers are triblock copolymers commonly used as excipients in pharmaceutical formulations. They have an ABA type structure consisting of polyoxyethylene (A) and polyoxypropylene (B). Since the polyoxypropylene midblock is more ...

 ————————————————————————————

Submit form to access full application note.

Key Words:

  • Viscosity
  • Temperature sweep
  • Triblock copolymer
  • Polymeric excipient
  • Poloxamer/Lutrol
  • Thermosensitive polymers
  • Self-assembly
  • Concentration dependence
Application Note Download Form

Banner Image.png

News & Articles


Automated Viscometer Standard Protocols

The RheoSense VROC® initium one plus automated viscometer is revolutionizing material characterization with just the push of a button. The research an...

More Than Meets the Eye

Dry eye, a medical condition that is associated with a lack of lubrication on the eye surface, is a chronic problem for many people. According to The ...

Automate Your Extensional Measurements

We are excited to announce that you are now able to run extensional viscosity measurements on the VROC initium one plus automated viscometer!  Extensi...

2022 Kickoff Checklist

Santa may be done with his list, but now it is time for all of us coming back to the office from the holidays to take care of ours. We have our checks...

Google+