
PepTalk 2021: Probing Protein Aggregation
Webinar
RheoSense Principal Scientist, Dr. Stacey Elliott, presented "Probing Protein Aggregation with Shear Rate & Temperature Dependent Viscosity Measurements" at the PepTalk Virtual Conference in January of 2021.
Viscosity measurements reflect changes in PPI and the resulting microstructure. Cluster arrangements commonly formed by inherently attractive proteins have a predictable effect on shear rate and temperature dependent viscosity measurements. We illustrate these effects with model protein solutions formulated with individual amino acid excipients to modify PPI and aggregate structure.
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