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Single-Point Intrinsic Viscosity
Intrinsic Viscosity of Polymer and Bio-Polymer Solutions
In previous applications, we have discussed how to measure Intrinsic Viscosity with m-VROC® and microVISC™. Intrinsic Viscosity can be used as a means to establish molecular size, structure and conformation of solute molecules in a given environment. In order to make intrinsic viscosity measurements faster and easier, the number of viscosity measurements can be reduced to a single concentration. In this study we present a comparison of Single-point and Multi-point Intrinsic viscosity methods for a number of polymers and bio-polymers.
Our results show how, thanks to the superior repeatability of VROC® powered systems, both Single-point and Multi-point intrinsic viscosity measurements present good correlation. This allows Intrinsic Viscosity to be used as a fast and easy Q&C indicator with impresive sensitivity to molecular interaction. Remember Intrinsic Viscosity opens the door to the characterization of:
- Molecular Size and Weight
- Structure
- Conformation and Melting Temperature of Protein Solutions
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