Concentrated protein solutions are widely used in biopharmaceutical research and development. Protein-based drugs are the fastest growing class of drugs for the treatment of many diseases in humans, ranging from cancer to Alzheimer’s disease.
Single point viscosity measurements of complex fluids can suffice for quality control or screening purposes if the shear rate is chosen carefully or if the formulation is confirmed Newtonian. However, it is advantageous to explore the shear rate dependence of protein solutions to understand solution stability, efficacy, and overall performance. A thorough viscosity analysis of protein formulations should include both shear rate and temperature variation.
Download our Multi Point Viscosity Measurements of Proteins eBook for a complete guide to understanding what information can be obtained if more than a single point viscosity measurement is performed.